Comparison of Casein Phosphopeptide with Potassium Nitrate and Sodium Monofluorophosphate Desensitizing Efficacy after In-Office Vital Bleaching—A Randomized Trial

Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), potassium nitrate, and sodium monofluorophosphate are desensitizing agents that help in reducing teeth sensitivity. However, indecisive evidence exists regarding their efficacy. Therefore, this study was conducted to compare the efficacy of casein nitrate with after in-office vital bleaching. A randomized controlled trial on 2011 patients. The patients were randomly equally divided into CPP-ACP group (group 1), 2), placebo gel 3). upper lower anterior including first premolar isolated a rubber dam, then bleaching applied labial surface all teeth, followed by light activation for 15 min. procedure repeated 3 times an interval 5 min in-between. After carrying out procedure, given or unmarked syringes instruction apply it every 12 h up days. intensity pain recorded using discomfort scale (DIS). decrease observed 24 application groups 1 2. 3, persisted, 46 (69.69%) having moderate 14 (21.21%) developing severe over time. significant difference level time noted (p = 0.015) 2 0.036). no found 0.085). It concluded both performed exceptionally well